Pixologic ZBrush

With ZRemesher, you can spend more time being creative!

ZBrush 4R6 continues to improve and enhance ZBrush functionality by giving you access to an enriched toolset of new features which will increase your creativity and productivity. The new ZRemesher provides entirely rebuilt retopology system to give even better automated and user guided topology. There are also new brushes and functions to improve your workflow for both organic and hard surface sculpting.
ZRemesher is the next evolution in our 
automatic retopology solution. ZRemesher has 
been designed with an artist’s point of view

in mind. With a single click, ZRemesher 
produces ideal new topology based on your 
original mesh.
The new functions in ZRemesher are smarter, 
able to analyze the curvature of your model
with the precision of a computer, but with
the subtlety of the human eye.
Add more polygons locally where needed,
changing their shape to create perfect 
topology flow. As with most ZBrush tools,
ZRemesher also lets you take control 
over the automatic process and give
your own guidance to the core 
algorithms. It is easy to drive the flow
of polygons with the help of curves. You 
can also define where you wish to have
more or lower polygon density. You can 
perform local retopology to a specific
part of your mesh while keeping a natural 
connection with the support model.
By default, ZRemesher gives the Adaptive Size setting higher priority than the Target Polygon Count because of the Adaptive Density mode which is enabled by default.  But when this mode is disabeled, ZRemesher will adjust its topology calculations to give equal weight to your Target Polygon Count value. 
Other Additions
The new additions and improvements don't stop there! Here is a brief summary of other noteworthy new functions:
DynaMesh now preserves PolyGroups. This makes it so easy to do Panel or Group Looping on a DynaMesh after having used Mesh Insert or Mesh Fusion!
The Slice brushes now only operate on the curve position and won't propagate. What you see is now exactly what you get!
Group Front -- a new PolyGroup creation function -- detects all polygons which face the camera and assigns them to a single group. This tool will let you create special effects by using your point of view, such as deformation of only the parts of your model that are visible to the camera.
New Brushes
ZBrush’s powerful creative toolset is largely based on its brush system. With each release we add new brushes that can transform your way of working or simply make your daily sculpting easier. With ZBrush 4R6, we continue this long tradition.
The new Trim Curve brushes cut your models in a way that is very similar to the Clip brushes, but deletes the affected polygons rather than pushing them to the stroke line. And as you can imagine, these new brushes will be DynaMesh’s new best friends!
Creating holes through a mesh has been possible since the introduction of DynaMesh and more recently enhanced with Mesh Fusion. Now ZBrush adds another option for this purpose with the Bridge Curve brush: select an opening, PolyGroup border or crease edge and connect it with another to generate a bridge of polygons. And because this new topology detection is so useful with the Frame Mesh feature, we went ahead and enabled it for all brushes that use curves. You will love it as much as we do!
The new Solo Dynamic mode keeps only the current active SubTool visible when manipulating it in front of the ZBrush camera, in order to improve 3D navigation.
Internal UV Smoothing has been updated to freeze the UV borders.
And of course, a lot more!


In this video by Pixologic, the Z Spheres modelling tool is demonstrated:
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